Table 3. Comparative Analysis of Aldimine–Aryl Nitromethane Reactant Pairs in the Catalyzed Aza-Henry Reaction^a,b.

^aAll reactions employed 1.1 equiv of nitroalkane in toluene (0.1 M) at −20 °C with 24–36 h reaction time.

^bCatalyst prepared from (R,R)-cyclohexanediamine or (S,S)-cyclohexanediamine (denoted ent). Diastereomeric ratio (dr) and enantiomeric excess (ee) were determined by chiral HPLC following vacuum filtration or silica column chromatography (see the Supporting Information). All yields presented are isolated yields.