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Comparison of androstenedione and T changes for participants taking three divided doses of hydrocortisone 20 mg/d (ie, three times a day, 10–5–5) (left) or two divided doses of hydrocortisone 20 mg/d (ie, twice a day, 10–0–10) (right) plus abiraterone acetate at 100 mg/d (A and B) or 250 mg/d (C and D). Two participants changed from three times a day to twice a day therapy between the 100 and 250 mg/d abiraterone acetate treatment periods. AA, abiraterone acetate.
