Table 1.
Urinary Androsterone to Etiocholanolone Glucuronide Ratios
| Participant | Abiraterone Acetate 100 mg/d Treatment Period |
Abiraterone Acetate 250 mg/d TreatmentPeriod |
||
|---|---|---|---|---|
| Basal | Mean (Range) | Basal | Mean (Range) | |
| 200102 | 1.5 | 1.9 (1.5–2.2) | 1.2 | 1.0 (0.3–1.7)a |
| 200105 | 1.9 | 2.0 (1.8–2.1) | 1.5 | 1.3 (1.2–1.4) |
| 200106 | 1.4 | 1.7 (1.5–1.9) | 1.1 | 1.0 (0.7–1.3)a |
| 200111 | 1.9 | 2.2 (2.0–2.9) | 1.9 | 1.7 (1.3–2.0) |
| 200114 | 2.3 | 2.4 (2.0–2.7) | 1.5 | 1.6 (1.4–1.8) |
| 200115 | 1.5 | 1.4 (1.1–1.5) | 1.1 | 0.9 (0.7–1.3) |
a
Patients had two or more low androsterone glucuronide values on day 6, less than 250 μg/g creatinine.