Table 2.
Overall Daytime Period |
P Valueb | ||
---|---|---|---|
10 h in Bed | 4 h in Bed | ||
Plasma ACTH | |||
Number of peaks | 8 (5; 9) | 9 (5; 9) | .86 |
Trough value, pg/mL | 5 (3; 8) | 10 (4; 13) | .04 |
Peak value, pg/mL | 11 (9; 17) | 15 (9; 21) | .05 |
Absolute increment, pg/mL | 7 (4; 7) | 7 (6; 8) | .64 |
Serum total cortisol | |||
Number of peaks | 6 (5; 7) | 7 (6; 8) | .23 |
Trough value, μg/dL | 5 (4; 7) | 6 (5; 7) | .31 |
Peak value, μg/dL | 7 (7; 11) | 9 (9; 10) | .22 |
Increment, μg/dL | 3 (2; 3) | 3 (3; 4) | .24 |
Salivary free cortisol | |||
Number of peaks | 5 (3; 7) | 5 (4; 6) | .74 |
Trough value, μg/dL | 0.6 (0.4; 0.8) | 0.6 (0.4; 0.8) | .97 |
Peak value, μg/dL | 1.0 (0.7; 1.2) | 0.9 (0.7; 1.1) | .83 |
Increment, μg/dL | 0.3 (0.2; 0.5) | 0.3 (0.2; 0.4) | .58 |
Overall sampling period was from 9:00 am to midnight for ACTH and total cortisol and from 2:00 pm to midnight for free cortisol, in the 10-hours-in-bed and 4-hours-in-bed conditions. Data are expressed as median (quartile 1; quartile 3).
P values are from the Wilcoxon exact rank test.