Table 2.
Pre- and Postdrug Measurements of Spatiotemporal Parameters of Gait at Fastest and Fastest Matched Speeds During Treadmill Ambulation
| SSRI | 5HT antagonist | |||||
|---|---|---|---|---|---|---|
| Pre | Post | p value | Pre | Post | p value | |
| Fastest speed | ||||||
| Stride length (m) | 1.17±0.16 | 1.09±0.16 | 0.04 | 1.19±0.16 | 1.08±0.23 | 0.07 |
| Cadence (steps/min) | 75.2±28.6 | 72.7±28.3 | 0.30 | 76.3±29.0 | 68.9±32.0 | 0.05 |
| Fastest matched speed | ||||||
| Stride length (m) | 1.12±0.19 | 1.09±0.16 | 0.16 | 1.08±0.22 | 1.09±0.22 | 0.71 |
| Cadence (steps/min) | 70.6±28.0 | 72.2±28.0 | 0.21 | 69.2±31.5 | 69.6±30.2 | 0.84 |
Comparisons of spatiotemporal measures at fastest matched speeds demonstrated no differences with either 5HT medication. At fastest speeds, decrease in stride length after SSRIs and cadence after 5HT antagonists approach significance (α=0.025). Values are means±standard deviation.