Table 3A.

Pre- and Postdrug Measurements of Peak Sagittal-Plane Joint Range of Motion of the Hip, Knee, and Ankle at Fastest Speed

	SSRI			5HT antagonist
Fastest	Pre	Post	p value	Pre	Post	p value
More impaired limb
Ankle dorsiflexion	15±8	22±10	0.01	19±7	19±9	0.82
Ankle plantarflexion	−23±11	−17±10	0.12	−22±11	−17±15	0.19
Knee flexion	−60±16	−56±16	0.53	−64±23	−61±15	0.61
Knee extension	−7±16	−5±18	0.9	−9±16	−6±12	0.34
Hip flexion	37±15	35±11	0.91	39±12	42±12	0.45
Hip extension	−17±17	−11±9	0.16	−10±7	−6±8	0.3
Hip-knee ACC	0.88±0.04	0.88±0.04	0.61	0.86±0.07	0.86±0.08	0.36
Less impaired limb
Ankle dorsiflexion	15±5.7	18±8.6	0.23	17±6.5	17±9.3	0.95
Ankle plantarflexion	−18±14	−10±14	0.06	−17±14	−15±12	0.47
Knee flexion	−57±7.5	−62±9.9	0.04	−60±8.4	−61±6.3	0.79
Knee extension	−3.1±15	−7.6±16	0.02	−4.3±16	−3.9±13	0.85
Hip flexion	35±16	42±6.7	0.24	39±9.0	44±9.9	0.34
Hip extension	−16±17	−7.9±9.1	0.12	−11±12	−7.3±8.1	0.58
Hip-knee ACC	0.88±0.08	0.90±0.07	0.33	0.89±0.07	0.88±0.09	0.88

Negative values represent plantarflexion at the ankle, flexion at the knee, and extension at the hip. Values are presented in degrees (mean±standard deviation).

SSRI, selective serotonin reuptake inhibitor; 5HT, serotonergic; ACC, average coefficient of correlation.