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. 2014 Aug 1;31(15):1334–1342. doi: 10.1089/neu.2013.3206

Table 3B.

Pre- and Postdrug Measurements of Peak Sagittal-Plane Joint Range of Motion of the Hip, Knee, and Ankle at Fastest Matched Speed

  SSRI 5HT antagonist
Fastest matched Pre Post p value Pre Post p value
More impaired limb
 Ankle dorsiflexion 18±7 18±5 0.98 20±10 20±10 0.84
 Ankle plantarflexion −21±10 −16±13 0.07 −22±14 −23±14 0.70
 Knee flexion −60±13 −56±16 0.16 −62±19 −61±16 0.75
 Knee extension −6±16 −5±18 0.84 −8±15 −6±12 0.44
 Hip flexion 37±14 35±11 0.75 38±11 42±12 0.29
 Hip extension −14±15 −11±9 0.38 −9±7 −6±8 0.48
 Hip-knee ACC 0.88±0.04 0.88±0.04 0.61 0.86±0.07 0.86±0.08 0.36
Less impaired limb
 Ankle dorsiflexion 16±6.2 18±7.8 0.16 18±6.2 17±10 0.57
 Ankle plantarflexion −12±11 −8.2±9.3 0.06 −14±14 −17±15 0.43
 Knee flexion −58±8.5 −62±10 0.09 −59±8.9 −60±6.6 0.51
 Knee extension −6.8±18 −11±19 0.07 −8.2±19 −6.9±16 0.39
 Hip flexion 35±16 41±6.7 0.27 38±7.4 42.6±7.4 0.18
 Hip extension −15±16 −7.6±8.9 0.18 −11±12 −7.3±7.4 0.32
 Hip-knee ACC 0.88±0.08 0.90±0.06 0.27 0.88±0.07 0.88±0.10 0.79

Negative values represent plantarflexion at the ankle, flexion at the knee, and extension at the hip. Values are presented in degrees (mean±standard deviation).

SSRI, selective serotonin reuptake inhibitor; 5HT, serotonergic; ACC, average coefficient of correlation.