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. Author manuscript; available in PMC: 2014 Aug 4.
Published in final edited form as: Anat Rec (Hoboken). 2010 Jun;293(6):968–981. doi: 10.1002/ar.21094

Figure 1.

Figure 1

Proteoglycans found in normal lungs. Perlecan, a HSPG, is found in the basal lamina of epithelial and endothelial cells. The CSPGs, versican and decorin, are found in the interstitial space of the lungs. Versican binds to the glycosaminoglycan, hyaluronan, to form high-molecular weight complexes. Decorin binds to collagen and helps stabilize the collagen-elastin network. Syndecans are membrane proteoglycans that interact with matrix proteins. This figure is not meant to represent the concentrations of the different proteoglycans in normal lungs and is meant to only show their approximate location in the alveolus. (This figure is from a chapter by Frevert, et al., (Frevert and Wight, 2006) with permission)