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. Author manuscript; available in PMC: 2015 Jul 15.
Published in final edited form as: Clin Cancer Res. 2014 May 21;20(14):3721–3729. doi: 10.1158/1078-0432.CCR-13-3405

Figure 2. Binding specificity.

Figure 2

A) AA3G-740 efficiently labeled PC3 cells that have high level of GRPR (black filled area). Co-incubation with bombesin prevented the binding, resulting in minimal cell fluorescence (gray filled area). B) Low GRPR expressing cells, LNCaP, showed minimal increase in fluorescence (grey filled area). C) Control agent, CAA3G-740 containing a scrambled binding sequence was not able to label PC3 cells (grey filled area). Black outline represent unstained cells in all three panels.