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. 2014 Aug 4;9(8):e102958. doi: 10.1371/journal.pone.0102958

Figure 3. The NMDA receptor NMR-1 is required for dopamine modulation of octanol response.

Figure 3

(A) nmr-1 is required for dopamine sensitivity. nmr-1 codes for a NMDA-like ionotropic glutamate receptor subunit expressed in premotor interneurons of the octanol avoidance circuit [39]. The ak4 allele is predicted null. (B) Transgenic expression of nmr-1(+) restores normal octanol response to nmr-1 mutants. nmr-1; [nmr-1(+)] is a previously published transgenic strain wherein [nmr-1(+)] refers to akEx118, a fully functional gfp::nmr-1 translational fusion under the control of the endogenous nmr-1 promoter that restores nmr-1 function in a different behavioral paradigm [39]. Also see Fig. 1 legend for technical details. ***p<0.0001; n.s., not significant.