Figure 5. The state probability density and total free energy for the coupled reactions of scheme 1 that includes a non-equilibrium thermodynamic stable state.

Parameters are given in Table 1, column 2. In this case, the equilibrium/most probable state on the abscissa at 0.20 n_B/N_total. The nonequilibrium steady state is located on the abscissa at 0.50 n_B/N_total, and is stable only because of the applied driving force of -2 Kcal Kcal/mol (Figure 7).