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. 2014 Aug 4;9(8):e103703. doi: 10.1371/journal.pone.0103703

Table 2. Patient characteristics: median values and univariate analyses (t, U, χ2, and Fisher's exact tests).

No. of patients (%) P value
Factor Median ACF (n = 60) NS (n = 60) (log-rank)
Age (years) 79 77.4±10.9 76.1±12.0 .53
Age (≥80 years) 28 (47%) 25 (42%) .092
Gender (female) 21 (35%) 23 (38%) .34
On admission
GCS 6/9/11/12/13/14/15 14 0/2/1/3/4/28/22 1/0/0/3/9/24/23 .64 (<14)
mRS 0/1/2/3/4/5 3 0/11/12/11/18/8 0/11/11/15/17/6 ≥.99 (≥3)
Dysarthria 16 (27%) 12 (20%) .51
Hemiparesis 57 (95%) 53 (88%) .32
Headache 17 (28%) 23 (38%) .33
Past history
Cerebrovascular accident 14 (23%) 9 (15%) .35
Diabetes mellitus 9 (15%) 14 (23%) .35
Hypertension 31 (52%) 32 (53%) ≥.99
Heavy drinking 14 (23%) 9 (15%) .35
Ischemic heart disease 7 (12%) 5 (8%) .76
Tumor 7 (12%) 6 (10%) ≥.99
Drug history (anticoagulant) 7 (12%) 6 (10%) ≥.99
Drug history (antiplatelet) 21 (35%) 13 (22%) .16
CT findings
Laterality (left) 29 (48%) 32 (53%) .72
Hyper/Iso/Hypo/Layer/Grad/Sep/Trab 12/9/5/8/5/7/14 12/5/7/8/6/8/14 .79–≥.99
Hematoma cavity volume (mL) 137 147±49 149±49 .76
Preoperative laboratory data
Leukocytes, ×109/L 6.60 7.21±2.77 7.01±2.68 .69
Thrombocytes, ×109/L 220 250±85 209±103 .02
PT-INR 1.00 1.02±0.096 1.00±0.095 .11
Complications
Transient postoperative delirium 12 (20%) 11 (18%) ≥.99
Urinary tract infection 3 (5%) 1 (2%) .62
Postoperative data
GCS (10/12/13/14/15) 15 0/1/1/16/42 1/1/0/18/40 .84 (<14)
mRS 0/1/2/3/4/5 1 30/10/4/7/9 23/15/5/8/8/1 ≥.99 (≥3)
Cavity volume (mL) on POD 1 63.9 71±32 69±40 .83
Cavity volume (mL) on POD 7 62.8 59±37 74±40 .028
Hospital stay (days) 8 9.5±4.0 10.5±7.2 .37

Values are the mean ± SD when appropriate. Significant values are featured with bold font. Three PT-INR values from the NS group (1 recurrent patient) and 2 PT-INR values from the ACF group were missing and were excluded from analysis. Abbreviations: ACF: Artificial cerebrospinal fluid, NS: Normal saline, GCS: Glasgow Coma Score, mRS: Modified Rankin scale, CT: Computed tomography, Hyper: Hyperdense, Iso: Isodense, Hypo: Hypodense, Layer: Layered, Grad: Gradation, Sep: Separated, Trab: Trabecular, PT-INR: International normalized ratio of prothrombin time, POD: Postoperative day.