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. 2014 Aug 4;9(8):e103703. doi: 10.1371/journal.pone.0103703

Table 3. Factors related to recurrence: univariate analyses (t, U, χ2, and Fisher's exact tests) and log-rank tests.

No. of patients (%) P value P value
Factor No rec (n = 109) Rec (n = 11) (univariate) (log-rank)
Age (years) 76.3±11.7 75.1±6.1 .025 .044 (≥80 y)
Gender (female) 38 (35%) 6 (55%) .34 .20
On admission
GCS 6/9/11/12/13/14/15 1/2/1/6/9/45/45 0/0/0/0/4/7/0 .26 (<14) .13 (<14)
mRS 0/1/2/3/4/5 0/21/21/25/29/13 0/1/2/1/6/1 .20 (≥3) .48 (≥3)
Dysarthria 23 (21%) 5 (46%) .13 .067
Hemiparesis 99 (91%) 11 (100%) .63 .31
Headache 38 (35%) 2 (18%) .33 .26
Past history
Cerebrovascular accident 19 (17%) 4 (36%) .22 .12
Diabetes mellitus 21 (19%) 2 (18%) ≥.99 .93
Hypertension 56 (51%) 7 (64%) .65 .44
Heavy drinking 21 (19%) 2 (18%) ≥.99 .91
Ischemic heart disease 12 (11%) 0 (0%) .60 .26
Tumor 12 (11%) 1 (9.1%) ≥.99 .84
Drug history (anticoagulant) 12 (11%) 1 (9.1%) ≥.99 .84
Drug history (antiplatelet) 31 (28%) 3 (27%) ≥.99 .93
CT findings
Laterality (left) 52 (48%) 9 (82%) .067 .03
Hyper/Iso/Hypo/Lay/Grad/Sep/Trab 23/15/9/15/10/13/24 1/1/1/1/1/2/4 .28–≥.99 .26–.96
Hematoma cavity volume (mL) 147±48 158±53 .45 .36
Preoperative laboratory data
Leukocytes (×109/L) 7.2±2.8 6.4±2.2 .39 .33 (>6.6)
Thrombocytes (×109/L) 234±97 186±80 .12 .037 (≤22.0)
PT-INR 1.01±0.09 1.03±0.12 .53 .80 (≥1.00)
Intraoperative irrigation solution
NS versus ACF 58 (53%) 2 (18%) .053 .027
Complications
Transient postoperative delirium 19 (17%) 4 (36%) .22 .10
Urinary tract infection 4 (3.7%) 0 (0.0%) ≥.99 .53
Postoperative data
GCS on POD 5, 10/12/13/14/15 1/1/1/18/78 0/1/0/6/4 ≥.99 (<14) .19 (<14)
mRS on POD 5, 0/1/2/3/4/5 51/21/7/14/15/1 2/4/2/1/2/0 ≥.99 (≥3) .94 (≥3)
Cavity volume (mL) on POD 1 69±36 79±32 .41 .74 (≥64)
Cavity volume (mL) on POD 7 63±38 97±31 .005 .044 (≥63)
Hospital stay (days) 9.8±5.3 11.6±10.2 .57 .81

Values are the mean ± SD when appropriate. Significant values are featured with bold font. Four PT-INR values from the non-recurrent group and 1 PT-INR value from the recurrent group were missing and were excluded from analysis. Abbreviations: Rec: Recurrence, GCS: Glasgow Coma Score, mRS: Modified Rankin scale, CT: Computed tomography, Hyper: Hyperdense, Iso: Isodense, Hypo: Hypodense, Lay: Layered, Grad: Gradation, Sep: Separated, Trab: Trabecular, PT-INR: International normalized ratio of prothrombin time, NS: Normal saline, ACF: Artificial cerebrospinal fluid, POD: Postoperative day.