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. 2014 Jul 10;2014:489382. doi: 10.1155/2014/489382

Table 1.

Effect of sildenafil on serum creatinine and urea as well as urinary albumin levels of gentamicin-induced nephrotoxicity in rats.

Group Creatinine 
mg/dL
Urea 
mg/dL
Albumin 
mg/dL
Control 0.53 ± 0.01 26.2 ± 0.24 0.36 ± 0.01
Sildenafil 0.55 ± 0.01 25.8 ± 0.17 0.34 ± 0.01
Gentamicin 3.1 ± 0.1∗° 139 ± 1.48∗° 4.05 ± 0.10∗°
Gentamicin + sildenafil 0.94 ± 0.01∗°× 59.6 ± 1.02∗°× 2.04 ± 0.06∗°×

Data are mean ± SEM of 6–8 rats. ∗,°,×Significantly different from control, sildenafil, and gentamicin groups, respectively, at P < 0.05.