Table 2.
Distribution and number of major colonic leukocytes during DSS-induced colitis in Eng +/+ and Eng +/− mice.
| Experimental day(s) | Percent CD45+ cells | |||||
|---|---|---|---|---|---|---|
| B cells | T cells | Myeloid cells | ||||
| Eng +/+ | Eng +/− | Eng +/+ | Eng +/− | Eng +/+ | Eng +/− | |
| 0 | 31 ± 5 | 35 ± 5 | 14 ± 1 | 13 ± 1 | 22 ± 3 | 19 ± 2 |
| 7–9 | 33 ± 1 | 35 ± 8 | 14 ± 1 | 14 ± 1 | 37 ± 1* | 32 ± 8 |
| 18–23 | 33 ± 2 | 26 ± 4 | 16 ± 1 | 16 ± 1 | 23 ± 1 | 30 ± 5# |
|
| ||||||
| Total number of cells (×106) | ||||||
| B cells | T cells | Myeloid cells | ||||
|
| ||||||
| 0 | 0.4 ± 0.1 | 0.5 ± 0.1 | 0.2 ± 0.01 | 0.2 ± 0.01 | 0.3 ± 0.02 | 0.3 ± 0.04 |
| 7–9 | 0.9 ± 0.1 | 1.6 ± 0.4 | 0.5 ± 0.1 | 0.6 ± 0.1 | 1.2 ± 0.2 | 1.5 ± 0.3 |
| 18–23 | 2.5 ± 0.3* | 2.3 ± 0.4* | 1.2 ± 0.2* | 1.5 ± 0.2* | 1.8 ± 0.2* | 2.9 ± 0.8* |
Results represent mean ± SEM (for both genotypes, N = 3 experiments for day 0, 5 for days 7–9 and 4 for days 18–23, with 3-4 mice/experiment). *P < 0.05 versus corresponding day 0, # P = 0.08 versus corresponding day 0.