Table 1. Two-point Lod scores (Z) for linkage between the ocular disease locus and markers on chromosome 9 listed in physical distance (Mb) from the short-arm telomere (9p-tel).
Marker (recombinant) | Mb | Z at recombination fraction (θ) = | |||||||
0.00 | 0.05 | 0.10 | 0.20 | 0.30 | 0.40 | ZMax | ΘMax | ||
D9S1804 | 35.96 | -∞ | 3.98 | 3.79 | 3.00 | 1.99 | 0.88 | 3.98 | 0.05 |
D9S1859 (IV:7, V:6, V:7) | 36.63 | -∞ | 4.11 | 3.94 | 3.17 | 2.14 | 0.99 | 4.11 | 0.05 |
D9S1874 | 37.22 | 6.76 | 6.13 | 5.47 | 4.08 | 2.62 | 1.17 | 6.76 | 0.00 |
D9S2148 | 38.30 | 5.18 | 4.76 | 4.27 | 3.19 | 1.99 | 0.81 | 5.18 | 0.00 |
rs2073478 (V:6) | 38.40 | -∞ | 0.16 | 0.32 | 0.34 | 0.26 | 0.14 | 0.36 | 0.16 |
TRPM3 (c.195A>G) | 73.48 | 9.51 | 8.75 | 7.96 | 6.23 | 4.30 | 2.14 | 9.51 | 0.00 |
D9S301 | 73.80 | 7.59 | 6.91 | 6.19 | 4.67 | 3.04 | 1.35 | 7.59 | 0.00 |
D9S1876 | 75.23 | 6.42 | 5.86 | 5.28 | 4.07 | 2.78 | 1.44 | 6.42 | 0.00 |
D9S175 | 77.95 | 8.05 | 7.37 | 6.65 | 5.12 | 3.48 | 1.73 | 8.05 | 0.00 |
D9S284 (III:4) | 78.09 | -∞ | 6.37 | 5.94 | 4.68 | 3.20 | 1.60 | 6.44 | 0.03 |
D9S276 | 78.51 | -∞ | 4.45 | 4.19 | 3.28 | 2.14 | 0.89 | 4.46 | 0.04 |
D9S1122 | 79.69 | -∞ | 2.39 | 2.69 | 2.52 | 1.93 | 1.05 | 2.71 | 0.12 |
D9S1123 | 80.42 | -∞ | 2.84 | 2.77 | 2.29 | 1.63 | 0.87 | 2.84 | 0.06 |