Table 1. Genotype frequencies.
Doxycycline treatment | Background strain | Obtained genotype frequencies (%) | |||
sm22α-rtTA+; tetop-LAG608G− | sm22α-rtTA−; tetop-LAG608G+ | sm22α-rtTA+; tetop-LAG608G+ | sm22α-rtTA−; tetop-LAG608G− | ||
D0 | C57BL/6J | 30.2 | 26.4 | 34.0 | 9.4 |
C57BL/6J; FVB/NCrl | 14.6 | 29.2 | 33.3 | 22.9 | |
E0 | C57BL/6J | 36.7 | 24.1 | 17.7 | 21.5 |
C57BL/6J; FVB/NCrl | 22.9 | 40.0 | 17.1 | 20.0 |
D0, mice supplied with doxycycline from the date of birth; E0, mice supplied with doxycycline during embryogenesis and postnatally; +, presence of transgene; −, absence of transgene. The expected frequency for each individual genotype was 25%.