A: Mean thickness of the primary melanoma according to age of patients with localized tumors (stages I/II) or regional nodal metastases (stage III)
F-test based on a mixed model: stage difference, F(1,7)=322.2, P<0.0001; Age difference: F(7,7)=19.2, P=0.0005
B: Mean mitotic rate in patients with localized melanoma (Stages I and II) and those with regional nodal metastases (Stage III) sorted by patient age by decade.
F-test based on a mixed model: stage difference, F(1,7)=268.3, P<0.0001; Age difference: F(7,7)=30.4, P=0.0001