. Author manuscript; available in PMC: 2014 Aug 4.

Published in final edited form as: Ann Surg Oncol. 2013 Jul 10;20(12):3961–3968. doi: 10.1245/s10434-013-3100-9

Table 1.

Multivariate Analysis of Prognosis Within Cohorts of Patient Age by Decade for Localized Melanoma (stage I and II) Chi-square (d.f.=1), P-value

Age (yr)	Number of patients	Thickness	Ulceration	Clark’s Level	Site	Gender	Mitotic Rate
<20 ^**	185	1.4 P=0.2401	3.2 (df=1) P=0.0759	0.1 (df=1) P=0.8125	5.6 (df=1) P=0.0177^*	4.3 (df=1) P=0.0386^*	0.1 (df=1) P=0.7947
20-	796	7.8 (df=3) P=0.0505^*	1.7 (df=1) P=0.1926	0.2 (df=1) P=0.6610	0.6 (df=1) P=0.4497	3.8 (df=1) P=0.0524	17.3 (df=3) P=0.0006^*
30-	1509	14.6 (df=3) P=0.0022^*	2.2 (df=1) P=0.1346	1.9 (df=1) P=0.1725	6.1 (df=1) P=0.0136^*	8.7 (df=1) P=0.0031^*	17.1 (df=3) P=0.0007^*
40-	1903	25.4 (df=3) P<0.0001^*	10.6 (df=1) P=0.0011^*	0.3 (df=1) P=0.6019	6.8 (df=1) P=0.0089^*	7.7(df=1) P=0.0055^*	8.6 (df=3) P=0.0344^*
50-	2073	32.2 (df=3) P<0.0001^*	8.4 (df=1) P=0.0038^*	1.7 (df=1) P=0.1936	3.1 (df=1) P=0.0784	4.2 (df=1) P=0.0406^*	21.7 (df=3) P<0.0001^*
60-	1924	25.9 (df=3) P<0.0001^*	22.0 (df=1) P<0.0001^*	0.3 (df=1) P=0.5544	8.4 (df=1) P=0.0038^*	7.9 (df=1) P=0.0050^*	15.3 (df=3) P=0.0016^*
70-	1392	13.6 (df=3) P=0.0034^*	7.9 (df=1) P=0.0049^*	1.4(df=1) P=0.2429	3.5 (df=1) P=0.0629	0.3 (df=1) P=0.5819	11.7 (df=3) P=0.0083^*
≥80^**	451	9.2 (df=1) P=0.0024^*	1.0 (df=1) P=0.3258	4.9 (df=1) P=0.0272^*	3.3 (df=1) P=0.0692	0.1 (df=1) P=0.7141	1.6 (df=1) P=0.2110

P<0.05

^**

For patients <20 or ≥80 years of age, tumor thickness was categorized as ≤2.0 or >2.0 mm, and mitotic rate was categorized as <5.0 or ≥5.0/mm², due to the smaller sample size. For other patients, tumor thickness was categorized as 0–1.00, 1.01–2.00, 2.01–4.00, or >4.00 mm; mitotic rate was categorized as <1, 1-, 5.0- or ≥10.0/mm².