Table II.
Grading of inflammation | Staging of fibrosis | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
|
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Groups | Nos. | 0 | 1 | 2 | 3 | 4 | 0 | 1 | 2 | 3 | 4 |
CTRL | 6 | 6 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 |
PSa,c | 7 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 2 | 5 |
PS + pcDNA3a,c | 6 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 2 | 4 |
PS + pcDNA3-rIL-10b,d | 7 | 4 | 3 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 0 |
HAI, rat liver histopathology; CTRL, normal control rats; PS, porcine serum-induced fibrotic rats treated with saline; PS + pcDNA3, porcine serum-induced fibrotic rats treated with pcDNA3; PS + pcDNA3-rIL-10, porcine serum-induced fibrotic rats treated with pcDNA3-rIL-10. Grading of inflammation:
P<0.01, compared to group CTRL;
P<0.01, compared to groups PS and PS + pcDNA3. Staging of fibrosis:
P<0.01, compared to group CTRL;
P<0.01, compared to groups PS and PS + pcDNA3.