Table I.

Physiological parameters.

Variables	Control (n=15)	Vehicle (n=16)	Probucol (n=15)	Cilostazol (n=15)	Probucol + cilostazol (n=16)
Body weight	25.90±0.73	32.71±1.05b	33.77±0.51	33.99±1.25	33.09±0.63
MABP	82.48±2.36	89.38±2.13a	85.17±3.09	87.34±1.77	85.34±2.12
pH	7.34±0.01	7.33±0.01	7.32±0.02	7.32±0.01	7.32±0.01
pO2	111.13±4.11	105.75±3.56	107.33±3.68	111.20±3.34	112.94±3.82
pCO2	41.56±1.62	38.76±1.21	41.05±1.68	33.38±1.40	39.67±0.20
Total cholesterol	261.67±5.24	546.33±33.05b	245.00±14.47c	531.67±16.29	242.00±13.05c
LDL-cholesterol	211.67±3.53	420.67±28.72b	185.67±18.77c	409.33±20.85	179.00±5.57c

Values are the mean ± SEM. Body weight is expressed in grams. MABP, pO₂ and pCO₂ are expressed in mmHg.

^aP<0.05 and

^bP<0.01 vs. age-matched ApoE KO without HFD (control);

^cP<0.01 vs. age- and diet-matched ApoE KO (vehicle).

MABP, mean arterial blood pressure; LDL, low-density lipoprotein; SEM, standard error of the mean; ApoE, apolipoprotein E; KO, knockout; HFD, high-fat diet.