Figure 2. Correlation between gene promoter methylation, tumor stage and location. (A) A correlation between stages and RASSF1A promoter methylation was found, and particularly stage I and III showed hypermethylation with respect to adenomas and/or other stages (P = 0.01). (B) Correlation between location and hMLH1 promoter methylation. We observed a significant difference between right colon and sigma/rectum (P = 0.04).