. 2014 Jan 31;9(4):621–633. doi: 10.4161/epi.27956

Table 2. Methylation data observed in CRC and adjacent healthy tissues in terms of numbers of methylated samples and percentage for each of the studied genes.

Total patients = 80 (Females = 34; Males = 46)	Cancer tissue N° (%)	Adjacent healthy tissue N° (%)
APC	39 (48.7)	37 (46.2)
MGMT	36 (45.0)	14 (17.5)^a
CDKN2A	24 (30.0)	5 (6.25)^a
hMLH1	13 (16.2)	1 (1.25)^a
RASSF1A	10 (12.5)	1 (1.25)^a

^a Significant difference CRC vs. Adjacent healthy tissue (P < 0.01, Chi square or Fisher Exact Test).