Table 3. Distribution of genotypes.
Polymorphisms | Total | Genotype frequencies | ||
---|---|---|---|---|
RFC1 80G > A | 93 | GG (32.3%) | GA (50.5%) | AA (17.2%) |
MTHFR 677C > T | 93 | CC (34.4%) | CT (47.3%) | TT (18.3%) |
MTHFR 1298 A > C | 94 | AA (55.3%) | AC (36.2%) | CC (8.5%) |
MTRR 66A > G | 94 | AA (41.5%) | AG (39.4%) | GG (19.1%) |
MTR 2756A > G | 94 | AA (72.3%) | AG (27.7%) | GG (0.0%) |
TYMS 1494 6bp ins/del | 92 | 6+6+ (34.8%) | 6+6- (51.1%) | 6-6- (14.1%) |
TYMS 28 bp repeats | 92 | 3R3R (33%) | 3R2R (46%) | 2R2R (21%)* |
DNMT3B -149C > T | 92 | CC (41.3%) | CT (44.6%) | TT (12.0%) |
DNMT3B -579G > T | 92 | GG (45.7%) | GT (44.6%) | TT (9.7%) |
For four patients the genotypes were 2R4R and for two other patients 3R4R and 3R5R, respectively.