Table 1. Comparison between TALEN- and Lentivirus-mediated transgenesis.
TALEN | Lentivirus | |
---|---|---|
cells transfected | 1.0×107 | 1.0×107 |
clone survived | 30 | 80 |
Clones with inducible GFP expression | 27 | 7 |
Efficiency | 70% | 9% |
In vitro silence | No | in neuron linage |
In vivo silence | No | in neuron linage |