Table 4.

Comparison in Subgroups at High Risk of Recurrence: 3-Year End Points on Per-Protocol Cohort

Subgroup	Total No. of Patients		Local Recurrence–Free Rate					Local Recurrence–Free Survival Rate					Overall Survival Rate
			SR		SRB		P*	SR		SRB		P*	SR		SRB		P*
	SR	SRB	No. of Patients	%	No. of Patients	%		No. of Patients	%	No. of Patients	%		No. of Patients	%	No. of Patients	%
Tumor margin < 1.0 cm	42	46	34	81	37	80	.95	29	69	30	65	.70	30	71	32	70	.85
Margin-to-tumor ratio < 1.0	70	67	60	86	57	85	.92	48	69	42	63	.47	50	71	44	66	.47
Staple line cytology positive	4	10	3	75	9	90	.47	2	50	6	60	.73	2	50	7	70	.48
Wedge resection	74	81	63	85	69	85	.99	48	65	55	68	.69	50	68	57	70	.71
Clinical nodule size > 2.0 cm	38	39	33	87	34	87	.96	25	66	26	67	.94	26	68	28	72	.75

Abbreviations: SR, sublobar resection; SRB, sublobar resection with brachytherapy.

^*χ² test.