Table 3.

Response Data

Response	Treatment Strata
	Platinum Sensitive (n = 80)				Platinum Refractory (n = 99)
	Arm A: Ziv-Aflibercept + Topotecan (n = 41)		Arm B: Topotecan (n = 39)		Arm A: Ziv-Aflibercept + Topotecan (n = 51)		Arm B: Topotecan (n = 48)
	No.	%	No.	%	No.	%	No.	%
CR	0	0	0	0	0	0	0	0
PR*	1	2	0	0	1	2	0	0
SD	14	34	7	18	12	24	7	15
DCR†	15	37	7	18	13	25	7	15
Progressive disease	18	44	29	74	29	57	33	69
Symptomatic deterioration	3	7	1	3	2	4	3	6
Early death	0	0	0	0	0	0	1	2
Assessment inadequate	5	12	2	5	7	14	4	8

Abbreviations: CR, complete response; PR, partial response; SD, stable disease; DCR, disease control rate.

^*Both partial responses were unconfirmed.

^†DCR = CR + PR + SD.