Table 4.
Changes in Exercise Capacity and 6-Minute Walk Distance (intention to treat)
| Variable | UC |
AT |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline |
Month 3 |
Month 12 |
P* | Baseline |
Month 3 |
Month 12 |
P* | P† | |||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||||
| Heart rate, beats · min–1 | 116 | 23 | 118 | 23 | 118 | 23 | .797 | 117 | 22 | 117 | 19 | 115 | 18 | .539 | .558 |
| VO2peak, mL · kg–1 · min–1 | 14.3 | 4.4 | 15.1 | 4.1 | 15.6 | 4.1 | .622 | 14.5 | 4.8 | 15.1 | 5.1 | 15.6 | 5.3 | .602 | .710 |
| VO2peak, L · min–1 | 1.2 | 0.4 | 1.3 | 0.4 | 1.3 | 0.4 | .361 | 1.2 | 0.5 | 1.3 | 0.5 | 1.3 | 0.5 | .560 | .528 |
| VO2peak at VT, mL · kg–1 · min–1 | 10.3 | 2.0 | 10.7 | 2.4 | 11.3 | 2.3 | .213 | 11.1 | 2.4 | 10.9 | 2.5 | 11.6 | 2.8 | .546 | .675 |
| RER | 1.09 | 0.12 | 1.11 | 0.13 | 1.12 | 0.11 | .620 | 1.09 | 0.10 | 1.13 | 0.11 | 1.11 | 0.14 | .039 | .383 |
| 6-Minute walk distance, m | 356 | 109 | 391 | 97 | 383 | 79 | .259 | 358 | 119 | 390 | 105 | 382 | 116 | .040 | .541 |
NOTE. Sample size for the usual care (UC) group: baseline, n = 43; month 3, n = 35; month 12, n = 29; for the aerobic training (AT) group: baseline, n = 46; month 3, n = 42; month 12, n = 31.
Abbreviations: RER, respiratory exchange ratio; SD, standard deviation; VO2peak, peak oxygen consumption; VT, ventilatory threshold.
*
P value comparing the three time points (derived from an unadjusted model). Significant P values indicate that at least one time point is different.
†
P value for the interaction between time and treatment.