Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 26;14:34. doi: 10.1186/s12861-014-0034-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Sharma et al.; licensee BioMed Central Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

RNA expression levels of the Class 3 Semaphorin receptors in the rat retina during development. Receptors: Nrp1 transcript levels are around twofold higher than the peak level of Nrp2. Co-receptors: Plxna2 had the highest peak expression levels, and L1cam the lowest. Plxna2 and Plxna3 expression levels are very similar, with Plxna2 having around fourfold higher peak levels. Nrp2: RNA levels are lowest in the embryo, rising from P7 onwards and peaking at around fourfold higher in the adult. Plxna2: Expression peaks at birth at fivefold higher than at E16, drops again by P14 and is maintained at that level into the adult. Plxna3: RNA levels increase fourfold from E16 to their peak at birth before falling back to embryonic levels by P21. Plxna4a: Expression triples from E16 to P0, doubles again at P7, falls back one third by P21 before increasing again to peak in the adult. Error bars are SEM;^* p < 0.05; n = 4–5.