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. 2014 Jul 1;3(7):e172. doi: 10.1038/mtna.2014.25

Figure 2.

Figure 2

Dose-dependent induction of pUbC.Luc.122TS expression by co-injection with AmiR122. NMRI mice were injected hydrodynamically with increasing doses of AmiR122 together with a mix of two plasmids, 5 µg/animal of the luciferase expressing plasmid containing miR122-target sites (pUbC.Luc.122TS) and 1 µg/animal of the control plasmid expressing β-galactosidase (Bgal), lacking miR target sites. Each value represents the average of ratios between luciferase and Bgal measured on liver extract, 1 day after treatment, from three different animals (±SD).