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Dose-dependent effects of HLA-DRα1-MOG-35-55 on infarct volumes. Mice were subjected to 60 min-MCAO and followed by four daily treatments of vehicle (Tris–HCl) (n = 14), 100 μg (n = 12), 500 μg (n = 11), and 1 mg (n = 10) HLA-DRα1-MOG-35-55. The infarct volume was quantified as a percentage of the non-ischemic contralateral cortex, striatum, or hemisphere, respectively. Values are mean ± SEM. *P ≤ 0.05
