Fig. 6.

Ultrasonic vocalizations before and after MCAO. Measurements at post-MCAO day 3 of total calls, call duration, and bandwidth are shown as a percentage of the baseline (pre-surgery recording). Asterisk indicates that both MCAO groups demonstrate lower number of calls (MCAO vehicle vs. sham (P = 0.00); MCAO RTL1000 vs. sham (P = 0.00)) and shorter duration of calls as compared to sham-operated mice. (MCAO vehicle vs. sham (p = 0.00); MCAO RTL1000 vs. sham (p = 0.03)) RTL treatment, but not vehicle treatment, partially restores call duration to that of sham-operated mice. Number sign indicates MCAO RTL1000 different from MCAO VEH (p = 0.05) (sham (n = 5), MCAO VEH (n = 8)) MCAO RTL1000 (n = 8). Values are means ± SEM