Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Aug 4;6:183. doi: 10.3389/fnagi.2014.00183

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Hohman, Koran and Thornton-Wells.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

WDR11-AS1 (rs12261764) interaction is consistent between datasets. ADNI-1 data are presented in the top panel and ADNI-2/GO data are presented in the bottom panel. Biomarker groups are presented on the x-axis and annual change in the left inferior lateral ventricle is presented on the y-axis. Boxplots are grouped by rs12261764. G is the minor allele. The tau × rs7849530 interaction was statistically significant in both datasets (p ≤ 0.001). In ADNI-1, tau positive homozygous carriers of the G allele showed a greater rate of ventricular dilation than tau positive carriers of the T allele (p < 0.05), and the same trend was present in ADNI-2/GO (p = 0.059).