Table 3.
rs7849530 | Change statistics | ||||||||
---|---|---|---|---|---|---|---|---|---|
Model | AIC | R2 | Adj. R2 | Adj. R2 change | Adj. R2 change 95% CI# | F change | df1 | df2 | Sig. F Change (P-value) |
1a | 8463 | 0.360 | 0.352 | 0.352 | [0.30–0.39] | 47.87 | 8 | 681 | 3.29 × 10−61 |
2b | 8462 | 0.363 | 0.354 | 0.002 | [−0.001–0.013] | 2.83 | 1 | 680 | 0.092 |
3c | 8442 | 0.382 | 0.373 | 0.019 | [0.004–0.043] | 21.83 | 1 | 679 | 4.00 × 10−6 |
4d | 8444 | 0.384 | 0.373 | 0.000 | [−0.001–0.005] | 0.788 | 2 | 677 | 0.455 |
5e | 8406 | 0.419 | 0.408 | 0.035 | [0.011–0.070] | 40.798 | 1 | 676 | 3.14 × 10−10 |
Predictors: Constant, Intracranial Volume, Age, Education, Diagnosis, Gender, Biomarker Group.
Predictors: Constant, Intracranial Volume, Age, Education, Diagnosis, Gender, Biomarker Group, APOE.
Predictors: Constant, Intracranial Volume, Age, Education, Diagnosis, Gender, Biomarker Group, APOE, rs7849530.
Predictors: Constant, Intracranial Volume, Age, Education, Diagnosis, Gender, Biomarker Group, APOE, rs7849530, rs7849530 × Tau_only, rs7849530 × Both.
Predictors: Constant, Intracranial Volume, Age, Education, Diagnosis, Gender, Biomarker Group, eAPOE, rs7849530, rs7849530 × Tau_only, rs7849530 × Both, rs7849530 × Amyloid_only.
Ninety five percentage confidence interval calculated using a bootstrap procedure with 1000 replicates.