Table 4.

Comparison of 140-day CORT to 140-day CON septa (collagen content, ANP, BNP, and CNP gene expression) or left ventricle (mitochondrial DNA content and HNE and NAG protein modifications)

	Control	Cortisol
Collagen content	16.15 ± 2.12	14.0 ± 1.93
HNE-cytosolic	0.18 ± 0.01	0.16 ± 0.01
NAG-cytosolic	4.64 ± 0.36	4.37 ± 0.59
HNE-mitochondrial	0.38 ± 0.02	0.37 ± 0.02
NAG-mitochondrial	2.15 ± 0.28	2.49 ± 0.45
Nuclei/μm2 tissue	0.024 ± 0.001	0.025 ± 0.004
Mitochondrial DNA content	1.27 ± 0.05	0.40 ± 0.03*
ANP expression	1.08 ± 0.20	0.98 ± 0.18
BNP expression	1.03 ± 0.29	1.06 ± 0.19
CNP expression	1.32 ± 0.33	1.91 ± 0.29*

CORT, cortisol; CON, control.

^*Significantly different from control, P < 0.05.