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Long genes are biased toward decreased expression in psoriasis lesions regardless of expression profiling technology. Analyses shown in Fig. 3 were repeated, except genes were ordered and grouped into bins according to length. In F, we analyzed 1,770 genes with increased expression in lesional skin of patients after 4 wk of Enbrel therapy (FDR < 0.05 and FC > 1.50; red), along with 1,532 genes with decreased expression (FDR < 0.05 and FC < 0.67; blue) (GSE11903).
