Skip to main content
. 2014 Jun 6;307(3):H379–H390. doi: 10.1152/ajpheart.01002.2013

Fig. 4.

Fig. 4.

mDia2 contains a nuclear export sequence (NES) at the extreme COOH terminus. A: schematic of the GFP-mDia2 variants examined. B and C: localization of GFP-mDia2 NES variants in 10T1/2 cells 48 h posttransfection in the absence or presence of LMB as indicated. Scale bar = 20 μm. D: immunohistochemical localization of Flag-mDia2 variants containing a deletion or mutation of the conserved COOH-terminal leucine-rich region (inset: sequences). E: quantification of wild-type (Wt) and LL1064/5AA mDia2 localization. *Nuclear localization P < 0.05 vs. Wt.