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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2014 Apr 7;27(4):653–663. doi: 10.1111/pcmr.12238

Figure 4. Sequencing Detects Focal Deletions at High Resolution.

Figure 4

(A) CNV calls using SNP microarrays. (B) Sequencing coverage of PTEN exons in WM2664, PMWK, SKMEL24 and UACC257 with very low coverage in a PTEN deletion line (PMWK) as well as isolated exons in other lines (red arrowheads). (C) Aggregated mutation rates in selected tumor suppressor genes in cell lines using CGH array and sequencing.