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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2014 Apr 7;27(4):653–663. doi: 10.1111/pcmr.12238

Table 1. Selected Mutations in Melanoma Cell Lines and Patients.

Selected genes from melanoma cell lines and patient tumors with potential activating mutations.

Sample Gene Mutation Previously Observed?
Cell Line SKMEL100 KIT Y362F No
SBC12 PIK3CA K678E No
RPMI8322 KRAS G12V Yes
SKMEL78/88 HRAS G12V Yes
Patient Tumor RAM99-0621B KIT L255Q No
RAM00-0594B PIK3CA R88Q Yes
RAM99-0621B PIK3CA E545K Yes