Skip to main content
. 2014 Mar 5;1:14002. doi: 10.1038/mtm.2014.2

Figure 2.

Figure 2

Transduction profile of Rover, a puppy that received 0.75 × 1011 vg/g of RSV.AP Y731F AAV-6 at birth. Representative photomicrographs of AP histochemical staining in (a) skeletal muscles, (d) heart muscles, and (g) internal organs. Scale bar = 100 µm and it applies to all images. AP activity quantification results are shown for (b) skeletal muscles, (e) heart muscles, and (h) internal organs. The AAV genome copy number is shown for (c) skeletal muscles, (f) heart muscles, and (i) internal organs. AAV, adenoassociated virus; AP, alkaline phosphatase; BB, biceps brachii; BR, brain; CS, cranial sartorius; CT, cranial tibialis; DI, diaphragm; KI, kidney; LA, left atrium; LI, liver; LU, lung; LV, left ventricle; RV, right ventricle; RA, right atrium.