Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of pore helix mutations on ranolazine and lidocaine block of IhERG.
A. Fitted concentration–response relations for WT hERG (black line) and T623A hERG (grey line) inhibition by ranolazine (Ai) and lidocaine (Aii).
Panels B, and C show equivalent data for T624A, and V625A, respectively. Error bars for some points are small and are obscured by the symbols.
For all plots n ≥ 5 cells per data-point.
