Skip to main content
. 2014 Sep;74(100):220–230. doi: 10.1016/j.yjmcc.2014.05.013

Fig. 4.

Fig. 4

Effect of pore helix mutations on ranolazine and lidocaine block of IhERG.

A. Fitted concentration–response relations for WT hERG (black line) and T623A hERG (grey line) inhibition by ranolazine (Ai) and lidocaine (Aii).

Panels B, and C show equivalent data for T624A, and V625A, respectively. Error bars for some points are small and are obscured by the symbols.

For all plots n ≥ 5 cells per data-point.