Table 1.
Time | BP | pH | pO2 | pCO2 | Glucose | |
---|---|---|---|---|---|---|
Wild type | During tFCI | 90.2 ± 2.6 | 7.32 ± 0.01 | 118.4 ± 3.6 | 39.6 ± 2.4 | 125.6 ± 4.2 |
After tFCI | 86.4 ± 3.4 | 7.34 ± 0.02 | 121.3 ± 4.1 | 41.5 ± 2.3 | 135.1 ± 3.3 | |
Tg-Fat1 | During tFCI | 87.4 ± 2.5 | 7.34 ± 0.02 | 124.2 ± 3.8 | 40.8 ± 1.9 | 130.2 ± 3.6 |
After tFCI | 85.6 ± 3.8 | 7.33 ± 0.01 | 122.5 ± 3.4 | 42.0 ± 2.5 | 136.7 ± 3.4 |
Comparison of physiological parameters during and after transient focal cerebral ischemia (tFCI) in Tg-Fat1 mice and wild type littermates. Physiological parameters include: BP, mean blood pressure in mmHg; pO2, arterial O2 pressure in mmHg; pCO2, arterial CO2 pressure in mmHg; glucose, blood glucose levels in mg/dL. Data were obtained 10 min after the onset of tFCI (during) and 10 min of reperfusion (after), and expressed as mean ± SEM. n = 11 for wild type mice; n = 12 for Tg-Fat-1 mice.