TABLE 2.
Evaluation of Early Stat3 Activation in the Colons of ETBF-colonized C57Bl/6 Mice Compared with Controls
| Sham |
NTBFa |
ETBF |
||||
|---|---|---|---|---|---|---|
| Time Point | ICs | CECs | ICs | CECs | ICs | CECs |
| 6 h | ||||||
| Mean ± SEMa | 0.67 ± 0.4 | 0.0 | 1.1 | 0.0 | 0.61 ± 0.1 | 0.0 |
| Range | 0–1.5 | N/A | N/A | N/A | 0–1.5 | N/A |
| N | 3 | 3 | 2 | 2 | 9 | 9 |
| 16 h | ||||||
| Mean ± SEM | 0.5 ± 0.3 | 0.0 | 0.1 | 0.0 | 1.0 ± 0.2b | 0.0 |
| Range | 0–1 | N/A | N/A | N/A | 0.5–2 | N/A |
| N | 3 | 3 | 2 | 2 | 8 | 8 |
| 24 h | ||||||
| Mean ± SEM | 0.17 ± 0.17 | 0.0 | 0.5 ± 0.5 | 0 ± 1 | 2.3 ± 0.4c | 2.3 ± 0.7 |
| Range | 0–0.5 | N/A | N/A | N/A | 0–3 | 1– 3 |
| N | 3 | 3 | 2 | 2 | 5 | 5 |
All results from 2 independent experiments.
a
For sample sizes of 2, individual values are shown.
b
P = 0.06 (6 h versus 16 h IC).
c
P = 0.17 (16 h versus 24 h IC).
ICs, mucosal immune cells; CECs, colonic epithelial cells; N/A, not applicable.