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. Author manuscript; available in PMC: 2014 Aug 5.
Published in final edited form as: JAMA Neurol. 2013 Feb;70(2):156–157. doi: 10.1001/jamaneurol.2013.772

Table. Select Randomized Controlled Trials of Exercise as Treatment for Symptoms of Parkinson Disease.

Source Funder Intervention No. Primary Outcomes Primary Conclusion
Shulman et al,1 2012 Michael J. Fox Foundation High-or low-intensity treadmill or stretching and resistance training 67 Gait speed High-or low-intensity treadmill and stretching and resistance improves gait speed
Li et al,5 2012 National Institute of Neurological Disorders and Stroke Tai chi, resistance training, or stretching 195 Balance testing Tai chi improves balance
Ashburn et al,6 2007 Action Medical Research, John and Lucille Van Geest Foundation Home physiotherapy 142 Falling rates Physiotherapy had a trend toward a reduction in falls
Schmitz-Hübsch et al,7 2006 German Parkinson patients’ organization (dPV) Qigong 56 UPDRS Qigong improved UPDRS scores
Ellis et al,8 2005 Not reported Physiotherapy and medication 68 Health questionnaire including mobility subscale Physiotherapy improves mobility subscale of health questionnaire
Protas et al,9 2005 Veteran Affairs Gait training 18 Gait parameters and reports of falls Gait training improves gait and balance and reduced falls
Hirsch et al,10 2003 Not reported Balance and resistance training or balance training alone 15 Balance and muscle strength Balance and resistance training improves balance and strength
Schenkman et al,11 1998 National Institute of Health, Claude D. Pepper Older Americans Independence Center, National Center for Research Resources Relaxation with muscle activation 51 Spinal flexibility and physical performance Relaxation, muscle activation improves flexibility, physical performance

Abbreviation: UPDRS, Unified Parkinson Disease Rating Scale.