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. Author manuscript; available in PMC: 2014 Oct 18.
Published in final edited form as: Science. 2014 Apr 18;344(6181):319–324. doi: 10.1126/science.1249766

Fig. 1. Radial distribution of myelin in the adult mouse neocortex.

Fig. 1

(A) Immunohistochemical staining of MBP and CUX1 in coronal sections of wild type adult neocortex. High magnifications of boxed areas show reduced levels of myelin in layer II/III (brackets). (B) PMAS lengths (arrowheads) in Golgi-Cox-labeled adult wild type cortex. Top, representative neurons in layer II/III and layer V. Bottom, scatter plot of PMAS length versus distance of neuronal cell bodies from the pia (n=72, R2= 0.61093). (C) 3D renderings of three representative neurons. The green and blue neurons were located in layer III–IV and the red neuron was in layer V. Myelin is shown in white. Ctx, cortex; Hip, hippocampus, Th, thalamus. Scale bars, 500 μm (A, low magnification), 100 μm (A, insets), 20 μm (B), 25 μm (C).