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. Author manuscript; available in PMC: 2014 Aug 5.
Published in final edited form as: J Neurosci Res. 2012 Dec 26;91(3):416–425. doi: 10.1002/jnr.23155

Fig. 5.

Fig. 5

α4β2 nAChRs are required for BMI and MLA mediated neuroprotection. The white bars, NMDA control, show the remaining PSs in slices treated with 0.5 mM NMDA for 10 min. A) The light gray bar shows the recovery of slices treated for 1 hour with 0.1 μM BMI, washed for another hour with ACSF before treatment with NMDA. The dark gray bar shows the effect of 1 μM DHβE coapplied with 0.1 μM BMI. BMI significantly increased the recovery of PSs over NMDA controls and over BMI coapplied with DHβE (N=21;*, p<0.05). B) The light gray bar shows the neuroprotection by 10 nM MLA applied for 1 hour. Dark gray bar shows that 1 μM DHβE coapplied with 10 nM MLA prevented the neuroprotection (N=14;*p<0.05). See Fig 1 for design.