Table 3.
Means (SD) for main outcome measures 12 months after operation by treatment group (Kirschner wires or volar locking plate fixation), with estimated treatment effects after adjustment
| Wire | Plate | Treatment effect estimates | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) | No of patients | Mean (SD) | No of patients | Raw | Adjusted (95% CI)* | P value | |||
| Primary outcome PRWE score at 12 months in all participants | |||||||||
| All participants | 15.3 (15.8) | 211 | 13.9 (17.1) | 204 | −1.4 | −1.3 (−4.5 to 1.8) | 0.398 | ||
| Primary outcome PRWE score at 12 months in subgroups | |||||||||
| Age <50 | 13.2 (13.0) | 52 | 15.3 (16.3) | 49 | 2.0 | 1.4 (−5.0 to 7.8) | 0.338 | ||
| Age ≥50 | 16.0 (16.5) | 159 | 13.4 (17.4) | 155 | −2.6 | −2.2 (−5.8 to 1.4) | |||
| No IA extension | 16.7 (16.5) | 110 | 13.2 (16.1) | 105 | −3.5 | −3.3 (−7.6 to 1.1) | 0.211 | ||
| IA extension | 13.8 (14.9) | 101 | 14.7 (18.2) | 99 | 0.9 | 0.7 (−3.8 to 5.2) | |||
| Secondary outcomes at 12 months | |||||||||
| DASH | 16.2 (17.9) | 201 | 13.0 (15.6) | 195 | −3.3 | −3.2 (−6.5 to 0.0) | 0.051 | ||
| EQ-5D | 0.83 (0.19) | 204 | 0.85 (0.19) | 194 | 0.02 | 0.02 (−0.02 to 0.06) | 0.353 | ||
IA=intra-articular.
*Treatment effect estimate is difference between group means. Adjusted effect estimates from mixed effects regression based on complete case analysis with treatment group, age group, sex, and intra-articular extension as covariates (fixed effects) and recruiting centre as random effect; P values from analysis of variance (ANOVA) F test.