TABLE 4.
PFCs and Odds of an Endometriosis Diagnosis: Sensitivity Analyses for the Operative Sample
| Endometriosis Restricted to Stages 3 and 4 (n = 339) |
Comparison Group Restricted to Postoperative Diagnosis of a Normal Pelvis (n = 320) |
|||||
|---|---|---|---|---|---|---|
| PFCs (ng/ml) |
OR (95% CI) | Adjusteda
OR (95% CI) |
Adjustedb
OR (95% CI) |
OR (95% CI) | Adjusteda
OR (95% CI) |
Adjustedb
OR (95% CI) |
| PFOS | 1.94 (1.10–3.44) | 1.86 (1.05–3.30) | 1.50 (0.82–2.74) | 1.40 (0.92–2.14) | 1.27 (0.82–1.97) | 0.94 (0.58–1.52) |
| PFOA | 2.75 (1.26–6.02) | 2.58 (1.18–5.64) | 1.86 (0.81–4.24) | 1.97 (1.11–3.50) | 1.73 (0.96–3.10) | 1.06 (0.57–2.00) |
| PFNA | 1.45 (0.43–4.95) | 1.21 (0.35–4.19) | 0.99 (0.27–3.65) | 2.03 (0.84–4.89) | 1.56 (0.64–3.82) | 1.18 (0.46–3.05) |
| PFDA | 1.00 (0.10–10.3) | 0.72 (0.06–8.09) | 0.58 (0.04–7.42) | 4.43 (0.80–24.4) | 3.01 (0.53–17.0) | 1.74 (0.28–11.0) |
| PFHxS | 2.36 (0.97–5.76) | 2.12 (0.85–5.27) | 1.24 (0.47–3.31) | 1.45 (0.68–3.13) | 1.04 (0.46–2.35) | 0.41 (0.16–1.05) |
Excludes 22 women from the operative sample whose surgeries were cancelled, and 4 women from the population sample whose MRI were not readable for diagnostic purposes. Concentrations were log (x + 1) transformed for analysis; results are per logarithm unit change.
a
Adjusted for age (continuous) and body mass index (continuous).
b
Adjusted for age (continuous), body mass index (continuous), and parity conditional on gravity (never pregnant, pregnant without births, pregnant with births).