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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: J Comp Pathol. 2013 May 8;149(4):434–445. doi: 10.1016/j.jcpa.2013.03.008

Fig. 7.

Fig. 7

Transmission electron microscopy of the liver of a DMN-exposed medaka with oval cell hyperplasia. A row of oval cells (OC) is located between hepatocytes (H) and in contact with a bile preductular epithelial cell (BPDEC) and a cell showing features of hepatocyte differentiation (immature hepatocytes [IH]) including increased cell volume, increased nuclear size, greater number of mitochondria, increased glycogen and development of rough endoplasmic reticulum. A biliary canaliculus formed by a BPDEC and hepatocytes is visible (arrow). Junctional complexes are indicated by arrowheads. Bar, 2 μm.