Table 3.

Summary of Immunohistochemical Expression Analysis

Marker	Hepatocyte	Cholangiocyte	Oval cell	Oval cell with hepatocyte features	Myofibroblast and activated stellate cell
Cytokeratin AE1/AE3	−	+++	+++	(+)	−
RFP	+++	−	−	(+)	−
MSA	−	−	−	−	+++
PCNA (DMN exposure)	++	++	+	++	−
PCNA (MCLR exposure)	+	+	+++	+	−

RFP, red fluorescent protein; MSA, muscle specific actin; PCNA, proliferating cell nuclear antigen; DMN, dimethylnitrosamine; MCLR, microcystin LR.

Immunoreactivity scoring: − absent; (+) variable and mild; + mild; ++ moderate; +++ marked.